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DSCAM-AS1 Long Non-Coding RNA Exerts Oncogenic Functions in Endometrial Adenocarcinoma via Activation of a Tumor-Promoting Transcriptome Profile

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Treeck, Oliver ; Weber, Florian ; Fritsch, Juergen ; Skrzypczak, Maciej ; Schüler-Toprak, Susanne ; Buechler, Christa ; Ortmann, Olaf
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Date of publication of this fulltext: 31 Oct 2022 05:40


Accumulating evidence suggests that lncRNA DSCAM-AS1 acts tumor-promoting in various cancer entities. In breast cancer, DSCAM-AS1 was shown to be the lncRNA being most responsive to induction by estrogen receptor alpha (ER alpha). In this study, we examined the function of DSCAM-AS1 in endometrial adenocarcinoma using in silico and different in vitro approaches. Initial analysis of open-source ...


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