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DSCAM-AS1 Long Non-Coding RNA Exerts Oncogenic Functions in Endometrial Adenocarcinoma via Activation of a Tumor-Promoting Transcriptome Profile

URN to cite this document:
urn:nbn:de:bvb:355-epub-531368
DOI to cite this document:
10.5283/epub.53136
Treeck, Oliver ; Weber, Florian ; Fritsch, Juergen ; Skrzypczak, Maciej ; Schüler-Toprak, Susanne ; Buechler, Christa ; Ortmann, Olaf
[img]License: Creative Commons Attribution 4.0
PDF - Published Version
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Date of publication of this fulltext: 31 Oct 2022 05:40



Abstract

Accumulating evidence suggests that lncRNA DSCAM-AS1 acts tumor-promoting in various cancer entities. In breast cancer, DSCAM-AS1 was shown to be the lncRNA being most responsive to induction by estrogen receptor alpha (ER alpha). In this study, we examined the function of DSCAM-AS1 in endometrial adenocarcinoma using in silico and different in vitro approaches. Initial analysis of open-source ...

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