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Localization of natriuretic peptide receptors A, B, and C in healthy and diseased mouse kidneys

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Heinl, Elena-Sofia ; Broeker, Katharina Anna-Elisabeth ; Lehrmann, Claudia ; Heydn, Rosmarie ; Krieger, Katharina ; Ortmaier, Katharina ; Tauber, Philipp ; Schweda, Frank
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Date of publication of this fulltext: 13 Dec 2022 05:17

This publication is part of the DEAL contract with Springer.


The natriuretic peptides (NPs) ANP (atrial natriuretic peptide) and BNP (B-type natriuretic peptide) mediate their widespread effects by activating the natriuretic peptide receptor-A (NPR-A), while C-type natriuretic peptide (CNP) acts via natriuretic peptide receptor-B (NPR-B). NPs are removed from the circulation by internalization via the natriuretic peptide clearance receptor natriuretic ...


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