Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.

URN to cite this document:: urn:nbn:de:bvb:355-epub-534157
DOI to cite this document:: 10.5283/epub.53415

Simon, Michaela ; Gerlach, Roman G. ; Pfeifer, Yvonne ; Pfennigwerth, Niels ; Gatermann, Sören G. ; Schröder, Agnes

; Hiergeist, Andreas

; Hamprecht, Axel ; Rügamer, Tamara ; Gessner, André

; Jantsch, Jonathan

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 14 Dec 2022 13:14

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Abstract

Ceftazidime-avibactam is one of the last resort antimicrobial agents for the treatment of carbapenem-resistant, Gram-negative bacteria. Metallo-beta-lactamase-producing bacteria are considered to be ceftazidime-avibactam resistant. Here, we evaluated a semi-automated antimicrobial susceptibility testing system regarding its capability to detect phenotypic ceftazidime-avibactam resistance in 176 ...