Additional Diffusion-Weighted Imaging with Background Body Signal Suppression (DWIBS) Improves Pre-Therapeutical Detection of Early-Stage (pT1a) Glottic Cancer: A Feasibility and Interobserver Reliability Study

URN zum Zitieren dieses Dokuments:

urn:nbn:de:bvb:355-epub-534544 Copy

DOI zum Zitieren dieses Dokuments:

10.5283/epub.53454 Copy

Schleder, Stephan ; May, Matthias ; Habicher, Werner ; Dinkel, Johannes ; Schreyer, Andreas G. ; Gostian, Antoniu-Oreste ; Schicho, Andreas

Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (1MB)

Veröffentlichungsdatum dieses Volltextes: 23 Dez 2022 08:10

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Details

Dokumentenart:	Artikel
Open Access Art:	Gold (ohne APC)
Titel eines Journals oder einer Zeitschrift:	Diagnostics
Verlag:	MDPI
Ort der Veröffentlichung:	BASEL
Band:	12
Nummer des Zeitschriftenheftes oder des Kapitels:	12
Seitenbereich:	S. 3200
Datum:	16 Dezember 2022
Institutionen:	Medizin > Lehrstuhl für Röntgendiagnostik
Identifikationsnummer:	Wert Typ 10.3390/diagnostics12123200 DOI
Stichwörter / Keywords:	SQUAMOUS-CELL CARCINOMA; LARYNGEAL; HEAD; INVASION; NECK; CARTILAGE; ACCURACY; MRI; MRI; DWIBS; glottic cancer; staging
Dewey-Dezimal-Klassifikation:	600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
Status:	Veröffentlicht
Begutachtet:	Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:	Ja
Dokumenten-ID:	53454

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Zusammenfassung

(1) Background: Early-stage glottic cancer is easily missed on magnetic resonance imaging (MRI). Diffusion-weighted imaging (DWI) may improve diagnostic accuracy. Therefore, our aim was to assess the value of adding diffusion-weighted imaging with background body signal suppression (DWIBS) to pre-therapeutic MRI staging. (2) Methods: Two radiologists with 8 and 13 years of experience, blinded to ...

Zusammenfassung

(1) Background: Early-stage glottic cancer is easily missed on magnetic resonance imaging (MRI). Diffusion-weighted imaging (DWI) may improve diagnostic accuracy. Therefore, our aim was to assess the value of adding diffusion-weighted imaging with background body signal suppression (DWIBS) to pre-therapeutic MRI staging. (2) Methods: Two radiologists with 8 and 13 years of experience, blinded to each other's findings, initially interpreted only standard MRI, later DWIBS alone, and afterward, standard MRI + DWIBS in 41 patients with histopathologically proven pT1a laryngeal cancer of the glottis. (3) Results: Detectability rates with standard MRI, DWIBS only, and standard MRI + DWIBS were 68-71%, 63-66%, and 73-76%, respectively. Moreover, interobserver reliability was calculated as good (kappa = 0.712), very good (kappa = 0.84), and good (kappa = 0.69) for standard MRI, DWIBS only, and standard MRI + DWIBS, respectively. (4) Conclusions: Standard MRI, DWIBS alone, and standard MRI + DWIBS showed an encouraging detection rate, as well as distinct interobserver reliability in the diagnosis of early-stage laryngeal cancer when compared to the definitive histopathologic report.

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Metadaten zuletzt geändert: 16 Jan 2023 15:24

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