Go to content
UR Home

Experimental and computational analysis of the ancestry of an evolutionary young enzyme from histidine biosynthesis

URN to cite this document:
DOI to cite this document:
Kinateder, Thomas ; Drexler, Lukas ; Straub, Kristina ; Merkl, Rainer ; Sterner, Reinhard
Date of publication of this fulltext: 10 Jan 2023 08:27

This publication is part of the DEAL contract with Wiley.


The conservation of fold and chemistry of the enzymes associated with histidine biosynthesis suggests that this pathway evolved prior to the diversification of Bacteria, Archaea, and Eukaryotes. The only exception is the histidinol phosphate phosphatase (HolPase). So far, non-homologous HolPases that possess distinct folds and belong to three different protein superfamilies have been identified ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons