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Granulocyte concentrate splitting does not affect phenotype and function

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Koo, Sebastian ; Offner, Robert ; Haile, Sophie‐Marie ; Brosig, Andreas ; Hähnel, Viola ; Gruber, Michael ; Burkhardt, Ralph ; Ahrens, Norbert

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Date of publication of this fulltext: 15 Feb 2023 09:13

This publication is part of the DEAL contract with Wiley.


Background: More granulocyte concentrates (GCs) could be produced for more patients from the same donor if apheresis bags were split and stored for longer periods of time. Hence, we tested the hypothesis that splitting and extension of storage of GCs do not impair granulocyte function or viability. Study Design and Methods: Granulocyte apheresis concentrates were produced using modified ...


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