The Optimal Effective Concentration Combination (OPECC) as a Novel Method for Evaluating the Effects of Binary Application of Antibacterial Compounds

URN to cite this document:: urn:nbn:de:bvb:355-epub-539948
DOI to cite this document:: 10.5283/epub.53994

Hiller, Karl-Anton

; Wenzl, Verena ; Forster, Eva-Maria ; Cieplik, Fabian

; Maisch, Tim

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 29 Mar 2023 04:17

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Abstract

Combination therapies appear to be beneficial for preventing bacterial resistance to antibacterial approaches. The aim of this study was to define and determine an optimal effective concentration combination (OPECC) for binary application of antibacterial compounds. The antiseptics chlorhexidine (CHX), benzalkonium chloride (BAC), and cetylpyridinium chloride (CPC), as well as the antibiotic ...