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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-541554
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.54155
Diese Publikation ist Teil des DEAL-Vertrags mit Wiley.
Zusammenfassung
The synthetic neomycin-sensing riboswitch interacts with its cognate ligand neomycin as well as with the related antibiotics ribostamycin and paromomycin. Binding of these aminoglycosides induces a very similar ground state structure in the RNA, however, only neomycin can efficiently repress translation initiation. The molecular origin of these differences has been traced back to differences in ...
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