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Allgaier, Raphael ; Kandulski, Arne ; Gülow, Karsten ; Maier, Lars ; Müller, Martina ; Tews, Hauke Christian

Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose

Article

Allgaier, Raphael , Kandulski, Arne, Gülow, Karsten, Maier, Lars, Müller, Martina and Tews, Hauke Christian (2023) Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose. Drugs in R&D.

DOI to cite this document: 10.5283/epub.54194


Abstract

Background and objectiveMetamizole is a non-opioid ampyrone sulfonate compound with potent analgesic, antipyretic, and spasmolytic effects. Agranulocytosis is a rare life-threatening complication of metamizole.CaseHere, we present the case of a 62-year-old patient who developed agranulocytosis as well as hemolysis after a single administration of metamizole.ConclusionThis case illustrates the inherent allergic potential of metamizole and its effects on different hematopoietic cell types.



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Details

Item typeArticle
Journal or Publication TitleDrugs in R&D
PublisherSPRINGER INT PUBL AG
Open Access TypeDEAL (Springer Gold)
Place of PublicationCHAM
Date29 March 2023
Date of publication11 May 2023 05:21
InstitutionsMedicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Innere Medizin II
Identification Number
ValueType
10.1007/s40268-023-00415-9DOI
KeywordsDRUG-INDUCED AGRANULOCYTOSIS; RISK; SAFETY; CELLS;
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-541946
Item ID54194

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