OSCC in Never-Smokers and Never-Drinkers Is Associated with Increased Expression of Tumor-Infiltrating Lymphocytes and Better Survival

DOI to cite this document:: 10.5283/epub.54341

Fiedler, Mathias ; Off, Alisa ; Eichberger, Jonas ; Spoerl, Steffen ; Schuderer, Johannes G.

; Taxis, Juergen

; Bauer, Richard J. ; Schreml, Stephan

; Reichert, Torsten E. ; Ettl, Tobias

; Weber, Florian

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Date of publication of this fulltext: 09 Jun 2023 06:32

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Abstract

The aim of this study was to investigate the clinical, histopathologic, and immunologic differences of oral squamous cell carcinoma of never-smokers/never drinkers and smokers/drinkers. Immunohistochemical staining for CD4, CD8, FoxP3, CD1a, and p16 was performed in 131 oral squamous cell carcinomas from smokers/drinkers and never-smokers/never-drinkers. Associations of smoking/drinking status ...