Analysis of long-term mortality after total body irradiation-based and melphalan-based chemotherapy conditioning for acute myeloid leukemia

URN to cite this document:: urn:nbn:de:bvb:355-epub-544012
DOI to cite this document:: 10.5283/epub.54401

Gruber, Isabella

; Koelbl, Oliver ; Treutwein, Marius

; Zeman, Florian ; Herr, Wolfgang ; Holler, Ernst ; Edinger, Matthias ; Wolff, Daniel

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 26 Jun 2023 08:58

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Abstract

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option for selected patients with acute myeloid leukemia. Yet, the influence of total body irradiation (TBI)-based conditioning as compared to non-TBI-based conditioning on long-term mortality is unclear. We retrospectively evaluated outcomes after TBI-based (n = 91) and non-TBI-based conditioning ...