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Clinical relevance of cell‐free DNA during venovenous extracorporeal membrane oxygenation

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Lingel, Maximilian P. ; Haus, Moritz ; Paschke, Lukas ; Foltan, Maik ; Lubnow, Matthias ; Gruber, Michael ; Krenkel, Lars ; Lehle, Karla
Date of publication of this fulltext: 07 Aug 2023 14:33

This publication is part of the DEAL contract with Wiley.


Background Thrombosis remains a critical complication during venovenous extracorporeal membrane oxygenation (VV ECMO). The involvement of neutrophil extracellular traps (NETs) in thrombogenesis has to be discussed. The aim was to verify NETs in the form of cell-free DNA (cfDNA) in the plasma of patients during ECMO. Methods A fluorescent DNA-binding dye (QuantifFluor®, Promega) was used to ...


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