Clinical relevance of cell‐free DNA during venovenous extracorporeal membrane oxygenation

URN to cite this document:: urn:nbn:de:bvb:355-epub-545636
DOI to cite this document:: 10.5283/epub.54563

Lingel, Maximilian P. ; Haus, Moritz ; Paschke, Lukas ; Foltan, Maik

; Lubnow, Matthias

; Gruber, Michael

; Krenkel, Lars ; Lehle, Karla

License: Creative Commons Attribution Non-commercial No Derivatives 4.0
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Date of publication of this fulltext: 07 Aug 2023 14:33

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Abstract

Background Thrombosis remains a critical complication during venovenous extracorporeal membrane oxygenation (VV ECMO). The involvement of neutrophil extracellular traps (NETs) in thrombogenesis has to be discussed. The aim was to verify NETs in the form of cell-free DNA (cfDNA) in the plasma of patients during ECMO. Methods A fluorescent DNA-binding dye (QuantifFluor®, Promega) was used to ...