Can Exercise Enhance the Efficacy of Checkpoint Inhibition by Modulating Anti-Tumor Immunity?

URN to cite this document:: urn:nbn:de:bvb:355-epub-548837
DOI to cite this document:: 10.5283/epub.54883

Brummer, Christina ; Pukrop, Tobias

; Wiskemann, Joachim ; Bruss, Christina ; Ugele, Ines ; Renner, Kathrin

License: Creative Commons Attribution 4.0
PDF - Published Version
(2MB)

Date of publication of this fulltext: 20 Oct 2023 12:30

Alternative links to fulltext:DOI Publisher

Details

Preview

Indexed in

Export bibliographical data

Abstract

Simple Summary Tumors escape from the host immune control by upregulation of inhibitory immune checkpoints. Immune checkpoint inhibition (ICI) has become the standard of care for many cancer entities. However, several patients do not respond to ICI because of primary or secondary resistance. Patients not benefitting from checkpoint inhibitors frequently display an immunosuppressive tumor ...