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Complementary Tumor Diagnosis by Single Cell–Based Cytogenetics Using Multi‐marker Fluorescence In Situ Hybridization (mFISH)

URN to cite this document:
urn:nbn:de:bvb:355-epub-551159
DOI to cite this document:
10.5283/epub.55115
Brockhoff, Gero
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 07 Dec 2023 05:31

This publication is part of the DEAL contract with Wiley.


Abstract

Multi-color (or multi-marker) fluorescence in situ hybridization (mFISH) is a well-established, valuable, complementary tool for prenatal and pathological (tumor) diagnosis. A variety of chromosomal abnormalities, such as partial or total chromosomal gains, losses, inversions, or translocations, which are considered to cause genetic syndromes, can relatively easily be detected on a cell-by-cell ...

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