Go to content
UR Home

Fine-tuning the antigen sensitivity of CAR T cells: emerging strategies and current challenges

URN to cite this document:
urn:nbn:de:bvb:355-epub-551663
DOI to cite this document:
10.5283/epub.55166
Harrer, Dennis Christoph ; Li, Sin-Syue ; Kaljanac, Marcell ; Barden, Markus ; Pan, Hong ; Abken, Hinrich
[img]License: Creative Commons Attribution 4.0
PDF - Published Version
(1MB)
Date of publication of this fulltext: 05 Dec 2023 13:56



Abstract

Chimeric antigen receptor (CAR) T cells are “living drugs” that specifically recognize their target antigen through an antibody-derived binding domain resulting in T cell activation, expansion, and destruction of cognate target cells. The FDA/EMA approval of CAR T cells for the treatment of B cell malignancies established CAR T cell therapy as an emerging pillar of modern immunotherapy. ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons