Go to content
UR Home

Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine

URN to cite this document:
DOI to cite this document:
Ousingsawat, Jiraporn ; Centeio, Raquel ; Reyne, Nicole ; McCarron, Alexandra ; Cmielewski, Patricia ; Schreiber, Rainer ; diStefano, Gabriella ; Römermann, Dorothee ; Seidler, Ursula ; Donnelley, Martin ; Kunzelmann, Karl
[img]License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 18 Jan 2024 05:19


The Ca2+ activated Cl− channel TMEM16A (anoctamin 1; ANO1) is expressed in secretory epithelial cells of airways and intestine. Previous studies provided evidence for a role of ANO1 in mucus secretion. In the present study we investigated the effects of the two ANO1-inhibitors niclosamide (Niclo) and benzbromarone (Benz) in vitro and in vivo in mouse models for cystic fibrosis (CF) and asthma. In ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons