Rising Lysophosphatidylcholine Levels Post-Hepatitis C Clearance

URN to cite this document:: urn:nbn:de:bvb:355-epub-554717
DOI to cite this document:: 10.5283/epub.55471

Peschel, Georg ; Krautbauer, Sabrina ; Weigand, Kilian

; Grimm, Jonathan ; Höring, Marcus

; Liebisch, Gerhard

; Müller, Martina ; Buechler, Christa

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 29 Jan 2024 15:27

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Abstract

Hepatitis C virus (HCV) infection alters lysophosphatidylcholine (LPC) metabolism, enhancing viral infectivity and replication. Direct-acting antivirals (DAAs) effectively treat HCV and rapidly normalize serum cholesterol. In serum, LPC species are primarily albumin-bound but are also present in lipoprotein particles. This study aims to assess the impact of HCV eradication on serum LPC species ...