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Rising Lysophosphatidylcholine Levels Post-Hepatitis C Clearance

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Peschel, Georg ; Krautbauer, Sabrina ; Weigand, Kilian ; Grimm, Jonathan ; Höring, Marcus ; Liebisch, Gerhard ; Müller, Martina ; Buechler, Christa
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 29 Jan 2024 15:27


Hepatitis C virus (HCV) infection alters lysophosphatidylcholine (LPC) metabolism, enhancing viral infectivity and replication. Direct-acting antivirals (DAAs) effectively treat HCV and rapidly normalize serum cholesterol. In serum, LPC species are primarily albumin-bound but are also present in lipoprotein particles. This study aims to assess the impact of HCV eradication on serum LPC species ...


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