New insights into the genetics of mandibular retrognathism: novel candidate genes

URN to cite this document:: urn:nbn:de:bvb:355-epub-554960
DOI to cite this document:: 10.5283/epub.55496

Paddenberg-Schubert, Eva

; Küchler, Erika Calvano

; Bitencourt Reis, Caio Luiz ; Silva-Sousa, Alice Corrêa ; Kirschneck, Christian

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 06 Feb 2024 12:53

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Abstract

Purpose Mandibular retrognathism (MR) is a common skeletal malocclusion in humans with a strong genetic component. Single nucleotide polymorphisms (SNPs) in genes encoding epidermal growth factor (EGF) and EGF receptor (EGFR) could be involved in the etiology of mandibular retrognathism. Therefore, in this study, we investigated whether SNPs in the genes encoding for EGF and EGFR are associated ...