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Unique Metabolomic and Lipidomic Profile in Serum From Patients With Crohn’s Disease and Ulcerative Colitis Compared With Healthy Control Individuals

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Tews, Hauke Christian ; Schmelter, Franziska ; Kandulski, Arne ; Büchler, Christa ; Schmid, Stephan ; Schlosser, Sophie ; Elger, Tanja ; Loibl, Johanna ; Sommersberger, Stefanie ; Fererberger, Tanja ; Gunawan, Stefan ; Kunst, Claudia ; Gülow, Karsten ; Bettenworth, Dominik ; Föh, Bandik ; Maaß, Carlos ; Solbach, Philipp ; Günther, Ulrich L. ; Derer, Stefanie ; Marquardt, Jens U. ; Sina, Christian ; Müller, Martina
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Date of publication of this fulltext: 02 Feb 2024 15:47


Background: Accurate biomarkers for disease activity and progression in patients with inflammatory bowel disease (IBD) are a prerequisite for individual disease characterization and personalized therapy. We show that metabolic profiling of serum from IBD patients is a promising approach to establish biomarkers. The aim of this work was to characterize metabolomic and lipidomic serum profiles of ...


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