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Does Variant Histology Change Management of Non-muscle-invasive Bladder Cancer?

Burger, Maximilian ; Kamat, Ashish M. ; McConkey, David


A 52-yr-old man, 35 pack-year smoker, is diagnosed with two non-muscle-invasive urothelial tumors, pTa and pT1, the former upstaged to pT1 by a reference pathologist. Two possible treatment strategies include intravesical bacillus Calmette-Guerin (BCG) and/or primary or rescue cystectomy. The importance or even accurate existence of "variant histology" is put into perspective, and whether the ...


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