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An investigation of the diagnostic, predictive, and prognostic impacts of three colonic biopsy grading systems for acute graft versus host disease

Palaniyandi, Senthilnathan ; Kreft, Andreas ; Hippe, Katrin ; Wagner-Drouet, Eva Maria ; Ries, Isabelle ; Kandulski, Arne ; Büttner-Herold, Maike ; Neumann, Helmut ; Weber, Daniela ; Holler, Ernst ; Schindeldecker, Mario



Zusammenfassung

Acute graft versus host disease (aGvHD) is an important, life-threatening complication after allogeneic hematopoietic stem cell transplantation (alloHSCT). To investigate the value of multiple simultaneous colon biopsies in improving diagnostic accuracy in patients with aGvHD, we retrospectively analyzed 157 patients after alloHSCT. The biopsies were evaluated individually using three established ...

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