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The effect of gut microbiota on the intestinal lipidome of mice

Liebisch, Gerhard ; Plagge, Johannes ; Höring, Marcus ; Seeliger, Claudine ; Ecker, Josef



Abstract

Gut microbiota significantly influence the plasma and liver lipidome. An interconnecting metabolite is acetate generated after degradation and fermentation of dietary fiber by the gut micmbiota, which is metabolized in the liver into longer chain fatty acids and complex lipids reaching the circulation. Whether these systemic changes are accompanied by alternations of the intestinal lipidome is ...

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