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Enhanced production of pro-inflammatory cytokines and chemokines in Ethiopian cutaneous leishmaniasis upon exposure to Leishmania aethiopica

Chanyalew, Menberework ; Abebe, Markos ; Endale, Birtukan ; Girma, Selfu ; Tasew, Geremew ; van Zandbergen, Ger ; Ritter, Uwe ; Gadisa, Endalamaw ; Aseffa, Abraham ; Laskay, Tamás


The clinical course and outcome of cutaneous leishmaniasis (CL) vary due to the infecting Leishmania species and host genetic makeup that result in different immune responses against the parasites. The host immune response to Leishmania aethiopica (L. aethiopica), the causative agent of CL in Ethiopia, is poorly understood. To contribute to the understanding of the protective immune response in ...


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