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Sodium Iodate-Induced Degeneration Results in Local Complement Changes and Inflammatory Processes in Murine Retina

Enzbrenner, Anne ; Zulliger, Rahel ; Biber, Josef ; Pousa, Ana Maria Quintela ; Schäfer, Nicole ; Stucki, Corinne ; Giroud, Nicolas ; Berrera, Marco ; Kortvely, Elod ; Schmucki, Roland ; Badi, Laura ; Grosche, Antje ; Pauly, Diana ; Enzmann, Volker


Age-related macular degeneration (AMD), one of the leading causes of blindness worldwide, causes personal suffering and high socioeconomic costs. While there has been progress in the treatments for the neovascular form of AMD, no therapy is yet available for the more common dry form, also known as geographic atrophy. We analysed the retinal tissue in a mouse model of retinal degeneration caused ...


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