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Improved risk estimation of locoregional recurrence, secondary contralateral tumors and distant metastases in early breast cancer: the INFLUENCE 2.0 model

Völkel, Vinzenz ; Hueting, Tom A. ; Draeger, Teresa ; van Maaren, Marissa C. ; de Munck, Linda ; Strobbe, Luc J. A. ; Sonke, Gabe S. ; Schmidt, Marjanka K. ; van Hezewijk, Marjan ; Groothuis-Oudshoorn, Catharina G. M. ; Siesling, Sabine


Purpose To extend the functionality of the existing INFLUENCE nomogram for locoregional recurrence (LRR) of breast cancer toward the prediction of secondary primary tumors (SP) and distant metastases (DM) using updated follow-up data and the best suitable statistical approaches. Methods Data on women diagnosed with non-metastatic invasive breast cancer were derived from the Netherlands Cancer ...


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