Unveiling Luminescent IrI and RhI N‐Heterocyclic Carbene Complexes: Structure, Photophysical Specifics, and Cellular Localization in the Endoplasmic Reticulum

URN to cite this document:: urn:nbn:de:bvb:355-epub-564085
DOI to cite this document:: 10.5283/epub.56408

Daubit, Isabelle Marie ; Wortmann, Svenja

; Siegmund, Daniel ; Hahn, Stephan

; Nuernberger, Patrick

; Metzler‐Nolte, Nils

License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 29 Feb 2024 12:27

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Abstract

Complexes of Rh-I and Ir-I of the [M(COD)(NHC)X] type (where M=Rh or Ir, COD=1,5-cyclooctadiene, NHC=N-heterocyclic carbene, and X=halide) have recently shown promising cytotoxic activities against several cancer cell lines. Initial mechanism of action studies provided some knowledge about their interaction with DNA and proteins. However, information about their cellular localization remains ...