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FDG PET/CT to detect bone marrow involvement in the initial staging of patients with aggressive non-Hodgkin lymphoma: results from the prospective, multicenter PETAL and OPTIMAL>60 trials

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Kaddu-Mulindwa, Dominic ; Altmann, Bettina ; Held, Gerhard ; Angel, Stephanie ; Stilgenbauer, Stephan ; Thurner, Lorenz ; Bewarder, Moritz ; Schwier, Maren ; Pfreundschuh, Michael ; Löffler, Markus ; Menhart, Karin ; Grosse, Jirka ; Ziepert, Marita ; Herrmann, Ken ; Dührsen, Ulrich ; Hüttmann, Andreas ; Barbato, Francesco ; Poeschel, Viola ; Hellwig, Dirk
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 29 Feb 2024 12:28


Purpose Fluorine-18 fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG PET/CT) is the standard for staging aggressive non-Hodgkin lymphoma (NHL). Limited data from prospective studies is available to determine whether initial staging by FDG PET/CT provides treatment-relevant information of bone marrow (BM) involvement (BMI) and thus could spare BM biopsy (BMB). ...


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