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CXCL5, CXCL8, and CXCL10 regulation by bacteria and mechanical forces in periodontium

Rath-Deschner, Birgit ; Memmert, Svenja ; Damanaki, Anna ; de Molon, Rafael S. ; Nokhbehsaim, Marjan ; Eick, Sigrun ; Kirschneck, Christian ; Cirelli, Joni A. ; Deschner, James ; Jäger, Andreas ; Nogueira, Andressa V.B.


Objective: The aim of the present study was to evaluate the expressions of CXCL5, CXCL8, and CXCL10 in periodontal cells and tissues in response to microbial signals and/or biomechanical forces. Methods: Human gingival biopsies from inflamed and healthy sites were used to examine the chemokine expressions and protein levels by real-time PCR and immunohistochemistry. The chemokines were also ...


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