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Risk factors associated with positive surgical margins’ location at radical cystectomy and their impact on bladder cancer survival

Claps, Francesco ; van de Kamp, Maaike W. ; Mayr, Roman ; Bostrom, Peter J. ; Boormans, Joost L. ; Eckstein, Markus ; Mertens, Laura S. ; Boevé, Egbert R. ; Neuzillet, Yann ; Burger, Maximilian ; Pouessel, Damien ; Trombetta, Carlo ; Wullich, Bernd ; van der Kwast, Theo H. ; Hartmann, Arndt ; Allory, Yves ; Lotan, Yair ; Shariat, Shahrokh F. ; Zuiverloon, Tahlita C. M. ; Mir, M. Carmen ; van Rhijn, Bas W. G.



Abstract

Purpose To evaluate the risk factors associated with positive surgical margins' (PSMs) location and their impact on disease-specific survival (DSS) in patients with bladder cancer (BCa) undergoing radical cystectomy (RC). Methods We analyzed a large multi-institutional cohort of patients treated with upfront RC for non-metastatic (cT1-4aN0M0) BCa. Multivariable binomial logistic regression ...

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