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Screening for Fatal Traumatic Brain Injuries in Cerebrospinal Fluid Using Blood-Validated CK and CK–MB Immunoassays

Zwirner, Johann ; Anders, Sven ; Bohnert, Simone ; Burkhardt, Ralph ; Da Broi, Ugo ; Hammer, Niels ; Pohlers, Dirk ; Tse, Rexson ; Ondruschka, Benjamin



Abstract

A single, specific, sensitive biochemical biomarker that can reliably diagnose a traumatic brain injury (TBI) has not yet been found, but combining different biomarkers would be the most promising approach in clinical and postmortem settings. In addition, identifying new biomarkers and developing laboratory tests can be time-consuming and economically challenging. As such, it would be efficient ...

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