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Outcomes of Unmanipulated Haploidentical Transplantation Using Post-Transplant Cyclophosphamide (PT-Cy) in Pediatric Patients With Acute Lymphoblastic Leukemia

Ruggeri, Annalisa ; Galimard, Jacques-Emmanuel ; Paina, Olesya ; Fagioli, Franca ; Tbakhi, Abdelghani ; Yesilipek, Akif ; Navarro, José Maria Fernandez ; Faraci, Maura ; Hamladji, Rose-Marie ; Skorobogatova, Elena ; Al-Seraihy, Amal ; Sundin, Mikael ; Herrera, Concepcion ; Rifón, Jose ; Dalissier, Arnaud ; Locatelli, Franco ; Rocha, Vanderson ; Corbacioglu, Selim



Abstract

HLA-haploidentical transplantation (haplo-HCT) using post-transplantation-cyclophosphamide (PT-Cy) is a feasible procedure in children with malignancies. However, large studies on Haplo-HCT with PT-Cy for childhood acute lymphoblastic leukemia (ALL) are lacking. We analyzed haplo-HCT outcomes in 180 children with ALL. Median age was 9 years, and median follow-up was 2.7 years. Disease status was ...

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