Kirches, Elmar ; Sahm, Felix 
; Korshunov, Andrey ; Bluecher, Christina ; Waldt, Natalie ; Kropf, Siegfried ; Schrimpf, Daniel ; Sievers, Philipp ; Stichel, Damian ; Schüller, Ulrich ; Schittenhelm, Jens ; Riemenschneider, Markus J. ; Karajannis, Matthias A. ; Perry, Arie ; Pietsch, Torsten ; Boekhoff, Svenja ; Capper, David ; Beck, Katja ; Paramasivam, Nagarajan ; Schlesner, Matthias ; Brastianos, Priscilla K. ; Müller, Hermann L. ; Pfister, Stefan M. ; Mawrin, Christian
; Korshunov, Andrey ; Bluecher, Christina ; Waldt, Natalie ; Kropf, Siegfried ; Schrimpf, Daniel ; Sievers, Philipp ; Stichel, Damian ; Schüller, Ulrich ; Schittenhelm, Jens ; Riemenschneider, Markus J. ; Karajannis, Matthias A. ; Perry, Arie ; Pietsch, Torsten ; Boekhoff, Svenja ; Capper, David ; Beck, Katja ; Paramasivam, Nagarajan ; Schlesner, Matthias ; Brastianos, Priscilla K. ; Müller, Hermann L. ; Pfister, Stefan M. ; Mawrin, Christian 
Abstract
In contrast to adults, meningiomas are uncommon tumors in childhood and adolescence. Whether adult and pediatric meningiomas differ on a molecular level is unclear. Here we report detailed genomic analyses of 37 pediatric meningiomas by sequencing and DNA methylation profiling. Histologically, the series was dominated by meningioma subtypes with aggressive behavior, with 70% of patients suffering ...
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