Affo, Silvia 
; Nair, Ajay ; Brundu, Francesco ; Ravichandra, Aashreya ; Bhattacharjee, Sonakshi ; Matsuda, Michitaka ; Chin, LiKang ; Filliol, Aveline ; Wen, Wen ; Song, Xinhua ; Decker, Aubrianna ; Worley, Jeremy ; Caviglia, Jorge Matias ; Yu, Lexing ; Yin, Deqi ; Saito, Yoshinobu ; Savage, Thomas ; Wells, Rebecca G. ; Mack, Matthias ; Zender, Lars ; Arpaia, Nicholas ; Remotti, Helen E. ; Rabadan, Raul ; Sims, Peter ; Leblond, Anne-Laure ; Weber, Achim ; Riener, Marc-Oliver ; Stockwell, Brent R. ; Gaublomme, Jellert ; Llovet, Josep M. ; Kalluri, Raghu ; Michalopoulos, George K. ; Seki, Ekihiro ; Sia, Daniela ; Chen, Xin ; Califano, Andrea ; Schwabe, Robert F.
; Nair, Ajay ; Brundu, Francesco ; Ravichandra, Aashreya ; Bhattacharjee, Sonakshi ; Matsuda, Michitaka ; Chin, LiKang ; Filliol, Aveline ; Wen, Wen ; Song, Xinhua ; Decker, Aubrianna ; Worley, Jeremy ; Caviglia, Jorge Matias ; Yu, Lexing ; Yin, Deqi ; Saito, Yoshinobu ; Savage, Thomas ; Wells, Rebecca G. ; Mack, Matthias ; Zender, Lars ; Arpaia, Nicholas ; Remotti, Helen E. ; Rabadan, Raul ; Sims, Peter ; Leblond, Anne-Laure ; Weber, Achim ; Riener, Marc-Oliver ; Stockwell, Brent R. ; Gaublomme, Jellert ; Llovet, Josep M. ; Kalluri, Raghu ; Michalopoulos, George K. ; Seki, Ekihiro ; Sia, Daniela ; Chen, Xin ; Califano, Andrea ; Schwabe, Robert F. 
Zusammenfassung
Cancer-associated fibroblasts (CAF) are a poorly characterized cell population in the context of liver cancer. Our study investigates CAF functions in intrahepatic cholangiocarcinoma (ICC), a highly desmoplastic liver tumor. Genetic tracing, single-cell RNA sequencing, and ligand-receptor analyses uncovered hepatic stellate cells (HSC) as themain source of CAF and HSC-derived CAF as the dominant ...
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