Rodríguez‐Barrueco, Ruth 
; Latorre, Jessica ; Devis‐Jáuregui, Laura ; Lluch, Aina ; Bonifaci, Nuria ; Llobet, Francisco J. ; Olivan, Mireia ; Coll‐Iglesias, Laura ; Gassner, Katja ; Davis, Meredith L. ; Moreno‐Navarrete, José M. ; Castells‐Nobau, Anna ; Plata‐Peña, Laura ; Dalmau‐Pastor, Miki ; Höring, Marcus ; Liebisch, Gerhard ; Olkkonen, Vesa M. ; Arnoriaga‐Rodríguez, Maria ; Ricart, Wifredo ; Fernández‐Real, José M. ; Silva, José M. ; Ortega, Francisco J. ; Llobet‐Navas, David
; Latorre, Jessica ; Devis‐Jáuregui, Laura ; Lluch, Aina ; Bonifaci, Nuria ; Llobet, Francisco J. ; Olivan, Mireia ; Coll‐Iglesias, Laura ; Gassner, Katja ; Davis, Meredith L. ; Moreno‐Navarrete, José M. ; Castells‐Nobau, Anna ; Plata‐Peña, Laura ; Dalmau‐Pastor, Miki ; Höring, Marcus ; Liebisch, Gerhard ; Olkkonen, Vesa M. ; Arnoriaga‐Rodríguez, Maria ; Ricart, Wifredo ; Fernández‐Real, José M. ; Silva, José M. ; Ortega, Francisco J. ; Llobet‐Navas, David 
Abstract
The H19X-encoded miR-424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results in obesity, while increasing the pool of early adipocyte progenitors and hypertrophied adipocytes. Complementary loss and gain of function experiments and RNA sequencing ...
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