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Involvement of complement peptides C3a and C5a in osteoarthritis pathology

Schäfer, Nicole ; Grässel, Susanne


Osteoarthritis (OA) affects more than 500 million people worldwide and is among the five diseases in Germany causing the highest suffering of the patients and cost for the society. The quality of life of OA patients is severely compromised, and adequate therapy is lacking owing to a knowledge gap that acts as a major barrier to finding safe and effective solutions. Chronic, low-grade inflammation ...


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