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Energy Metabolism and Lipidome Are Highly Regulated during Osteogenic Differentiation of Dental Follicle Cells

Pieles, Oliver ; Höring, Marcus ; Adel, Sadiyeh ; Reichert, Torsten E. ; Liebisch, Gerhard ; Morsczeck, Christian ; Ogasawara, Toru


Dental follicle cells (DFCs) are stem/progenitor cells of the periodontium and give rise to alveolar osteoblasts. However, understanding of the molecular mechanisms of osteogenic differentiation, which is required for cell-based therapies, is delimited. This study is aimed at analyzing the energy metabolism during the osteogenic differentiation of DFCs. Human DFCs were cultured, and osteogenic ...


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