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Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Doxorubicin for 90 Minutes Versus 60 Minutes After Cytoreductive Surgery (CRS). Does the 30-Minute Difference Matter? A Comparative Study in a High Volume Centre

ACS, MIKLOS ; HALMY, LASZLO ; ISGANDAROVA, SABINA ; BLAJ, SEBASTIAN ; GERKEN, MICHAEL ; HORMANN, BERNHARD ; PISO, POMPILIU



Abstract

Background/Aim: This study compared the perioperative outcomes after the same combination of hyperthermic intraperitoneal chemotherapy (HIPEC) compounds when administered for 90 min vs. 60 min, while all other therapy variables remained constant. Patients and Methods: A total of 120 patients were included with peritoneal surface malignancy who underwent cisplatin (75 mg/m(2)) and doxorubicin (15 ...

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