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Dietary salt and myeloid NFAT5 (nuclear factor of activated T cells 5) impact on the number of bone-remodelling cells and frequency of root resorption during orthodontic tooth movement

Paddenberg, Eva ; Krenmayr, Bernhard ; Jantsch, Jonathan ; Kirschneck, Christian ; Proff, Peter ; Schröder, Agnes



Abstract

Purpose: The aim of the study was to investigate the impact of dietary salt and the osmoprotective tran-scription factor nuclear factor of activated T cells 5 (NFAT5) in myeloid cells on bone remodelling cells as osteocytes, osteoblasts and osteoclasts and on force-induced dental root resorptions in a mouse model. Methods: Control mice and mice lacking myeloid NFAT5 (nuclear factor of activated T ...

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