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Second Cancer After Additive Chemotherapy in Patients With Colon Cancer

Teufel, Andreas ; Li, Moying ; Gerken, Michael ; Ebert, Matthias P. ; Schlitt, Hans J ; Evert, Matthias ; Herr, Wolfgang ; Klinkhammer-Schalke, Monika


Second cancer development represents a potential long-term side effects of chemotherapeutic agents. We investigated a total of 2856 Patients with UICC-stage III/IV colon cancer and identified 223 patients who had developed a subsequent second cancer. A significantly increased risk for subsequent second cancer after adjuvant chemotherapy was not detected. Interestingly, second cancer rate was ...


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