Go to content
UR Home

Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography

Girard, Eric ; Lopes, Pedro ; Spoerner, Michael ; Dhaussy, Anne-Claire ; Prangé, Thierry ; Kalbitzer, Hans Robert ; Colloc'h, Nathalie


In this work, we experimentally investigate the allosteric transitions between conformational states on the Ras oncogene protein using high pressure crystallography. Ras protein is a small GTPase involved in central regulatory processes occurring in multiple conformational states. Ras acts as a molecular switch between active GTP-bound, and inactive GDP-bound states, controlling essential signal ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons