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Nano-Scale Mechanical Properties of the Articular Cartilage Zones in a Mouse Model of Post-Traumatic Osteoarthritis

Fleischhauer, Lutz ; Muschter, Dominique ; Farkas, Zsuzsanna ; Grässel, Susanne ; Aszodi, Attila ; Clausen-Schaumann, Hauke ; Alberton, Paolo



Abstract

Featured Application Nano-scale IT-AFM is a sensitive tool to monitor biomechanical changes during the course of PT-OA. Destabilization of the medial meniscus (DMM) surgery in mice is used to elucidate the mechanism of post-traumatic osteoarthritis (PT-OA). The study of cartilage biomechanics in PT-OA is important for understanding the pathophysiology of the condition. We used indentation-type ...

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