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Assessing the prevalence of S-shaped root canal and associated genes in humans

Küchler, Erika Calvano ; Stroparo, Jeferson Luis de Oliveira ; Matsumoto, Mirian Nakane ; Scariot, Rafaela ; Perin, Camila Paiva ; Roskamp, Liliane ; Menezes-Oliveira, Maria Angélica Hueb de ; Proff, Peter ; Kirschneck, Christian ; Baratto-Filho, Flares


Background: Multiple signaling molecules have been shown to play crucial roles in dental root develop-ment. Therefore, we aimed to investigate the prevalence of S-shaped roots and also to investigate, if single nucleotide polymorphisms (SNPs) in BMP2, BMP4 and SMAD6 are associated with this phenotype in hu-mans. Methods: This is a cross-sectional phenotype-genotype association study that used ...


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