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The Impact of Increased Maternal sFlt-1/PlGF Ratio on Motor Outcome of Preterm Infants

Middendorf, Lisa ; Gellhaus, Alexandra ; Iannaccone, Antonella ; Köninger, Angela ; Dathe, Anne-Kathrin ; Bendix, Ivo ; Reisch, Beatrix ; Felderhoff-Mueser, Ursula ; Huening, Britta



Abstract

BackgroundThe sFlt-1 (soluble fms-like tyrosine kinase-1)/PlGF (placental growth factor) ratio serves as a clinical biomarker to predict the hypertensive, placenta-derived pregnancy disorder pre-eclampsia which is often associated with placental dysfunction and fetal growth restriction. Additionally elevated levels also indicate an increased risk for prematurity. However, its predictive value for ...

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