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F18-FDG PET/CT imaging early predicts pathologic complete response to induction chemoimmunotherapy of locally advanced head and neck cancer: preliminary single-center analysis of the checkrad-cd8 trial

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Beck, M. ; Hartwich, J. ; Eckstein, M. ; Schmidt, D. ; Gostian, A. O. ; Müller, S. ; Rutzner, S. ; Gaipl, U. S. ; von der Grün, J. ; Illmer, T. ; Hautmann, M. G. ; Klautke, G. ; Döscher, J. ; Brunner, T. ; Tamaskovics, B. ; Hartmann, A. ; Iro, H. ; Kuwert, T. ; Fietkau, R. ; Hecht, M. ; Semrau, S.
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Date of publication of this fulltext: 29 Feb 2024 13:01


Aim In the CheckRad-CD8 trial patients with locally advanced head and neck squamous cell cancer are treated with a single cycle of induction chemo-immunotherapy (ICIT). Patients with pathological complete response (pCR) in the re-biopsy enter radioimmunotherapy. Our goal was to study the value of F-18-FDG PET/CT in the prediction of pCR after induction therapy. Methods Patients treated ...


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