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Gender Related Differences in the Clinical Presentation of Hypertrophic Cardiomyopathy—An Analysis from the SILICOFCM Database

Preveden, Andrej ; Golubovic, Miodrag ; Bjelobrk, Marija ; Miljkovic, Tatjana ; Ilic, Aleksandra ; Stojsic, Snezana ; Gajic, Dragan ; Glavaski, Mila ; Maier, Lars S. ; Okwose, Nduka ; Popovic, Dejana ; Barlocco, Fausto ; Ristic, Arsen ; MacGowan, Guy A. ; Olivotto, Iacopo ; Filipovic, Nenad ; Jakovljevic, Djordje G. ; Velicki, Lazar



Abstract

Background and Objectives: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease that affects approximately 1 in 500 people. Due to an incomplete disease penetrance associated with numerous factors, HCM is not manifested in all carriers of genetic mutation. Although about two-thirds of patients are male, it seems that female gender is associated with more severe disease ...

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