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Integrative medicine during the intensive phase of chemotherapy in pediatric oncology in Germany: a randomized controlled trial with 5-year follow up

Seifert, Georg ; Blakeslee, Sarah B. ; Calaminus, Gabriele ; Kandil, Farid I. ; Barth, Andrea ; Bernig, Toralf ; Classen, Carl Friedrich ; Corbacioglu, Selim ; Föll, Jürgen ; Gottschling, Sven ; Gruhn, Bernd ; vom Hoff-Heise, Claudia ; Lode, Holger N. ; Martin, David ; Nathrath, Michaela ; Neunhoeffer, Felix ; Pekrun, Arnulf ; Wulff, Beate ; Zuzak, Tycho ; Henze, Günter ; Längler, Alfred


Background Integrative medicine is used frequently alongside chemotherapy treatment in pediatric oncology, but little is known about the influence on toxicity. This German, multi-center, open-label, randomized controlled trial assessed the effects of complementary treatments on toxicity related to intensive-phase chemotherapy treatment in children aged 1-18 with the primary outcome of the ...


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