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Longitudinal Outcome over Two Decades of Unrelated Allogeneic Stem Cell Transplantation for Relapsed/Refractory Acute Myeloid Leukemia: An ALWP/EBMT Analysis

Nagler, Arnon ; Ngoya, Maud ; Galimard, Jacques-Emmanuel ; Labopin, Myriam ; Bornhäuser, Martin ; Stelljes, Matthias ; Finke, Jürgen ; Ganser, Arnold ; Einsele, Herman ; Kröger, Nicolaus ; Brecht, Arne ; Bethge, Wolfgang ; Edinger, Matthias ; Kulagin, Aleksandr ; Passweg, Jakob ; Blau, Igor Wolfgang ; Elmaagacli, Ahmet ; Schäfer-Eckart, Kerstin ; Platzbecker, Uwe ; Schroeder, Thomas ; Bunjes, Donald ; Tischer, Johanna ; Martin, Sonja ; Spyridonidis, Alexandros ; Giebel, Sebastian ; Savani, Bipin ; Mohty, Mohamad



Abstract

Purpose: We evaluated outcomes of unrelated transplantation for primary refractory/relapsed (ref/rel) acute myeloid leukemia (AML), comparing two cohorts according to the year of transplant, 2000-2009 and 2010-2019.Patients and Methods: Multivariable analyses were performed using the Cox proportional-hazards regression model.Results: 3,430 patients were included; 876 underwent a trans-plant ...

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