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Temporal trends in pulmonary arterial hypertension: results from the COMPERA registry

Hoeper, Marius M. ; Pausch, Christine ; Grünig, Ekkehard ; Staehler, Gerd ; Huscher, Doerte ; Pittrow, David ; Olsson, Karen M. ; Vizza, Carmine Dario ; Gall, Henning ; Distler, Oliver ; Opitz, Christian ; Gibbs, J. Simon R. ; Delcroix, Marion ; Ghofrani, H. Ardeschir ; Rosenkranz, Stephan ; Park, Da-Hee ; Ewert, Ralf ; Kaemmerer, Harald ; Lange, Tobias J. ; Kabitz, Hans-Joachim ; Skowasch, Dirk ; Skride, Andris ; Claussen, Martin ; Behr, Juergen ; Milger, Katrin ; Halank, Michael ; Wilkens, Heinrike ; Seyfarth, Hans-Jürgen ; Held, Matthias ; Dumitrescu, Daniel ; Tsangaris, Iraklis ; Vonk-Noordegraaf, Anton ; Ulrich, Silvia ; Klose, Hans



Abstract

Background Since 2015, the European pulmonary hypertension guidelines recommend the use of combination therapy in most patients with pulmonary arterial hypertension (PAH). However, it is unclear to what extent this treatment strategy is adopted in clinical practice and if it is associated with improved long-term survival. Methods We analysed data from COMPERA, a large European pulmonary ...

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