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Cholangiocarcinoma landscape in Europe: Diagnostic, prognostic and therapeutic insights from the ENSCCA Registry

Izquierdo-Sanchez, Laura ; Lamarca, Angela ; La Casta, Adelaida ; Buettner, Stefan ; Utpatel, Kirsten ; Klümpen, Heinz-Josef ; Adeva, Jorge ; Vogel, Arndt ; Lleo, Ana ; Fabris, Luca ; Ponz-Sarvise, Mariano ; Brustia, Raffaele ; Cardinale, Vincenzo ; Braconi, Chiara ; Vidili, Gianpaolo ; Jamieson, Nigel B. ; Macias, Rocio IR. ; Jonas, Jan Philipp ; Marzioni, Marco ; Hołówko, Wacław ; Folseraas, Trine ; Kupčinskas, Juozas ; Sparchez, Zeno ; Krawczyk, Marcin ; Krupa, Łukasz ; Scripcariu, Viorel ; Grazi, Gian Luca ; Landa-Magdalena, Ana ; Ijzermans, Jan NM. ; Evert, Katja ; Erdmann, Joris I. ; López-López, Flora ; Saborowski, Anna ; Scheiter, Alexander ; Santos-Laso, Alvaro ; Carpino, Guido ; Andersen, Jesper B. ; Marin, Jose JG. ; Alvaro, Domenico ; Bujanda, Luis ; Forner, Alejandro ; Valle, Juan W. ; Koerkamp, Bas Groot ; Banales, Jesus M.



Abstract

Background & Aims: Cholangiocarcinoma (CCA) is a rare and heterogeneous biliary cancer, whose incidence and related mortality is increasing. This study investigates the clinical course of CCA and subtypes (intrahepatic [iCCA], perihilar [pCCA], and distal [dCCA]) in a pan-European cohort. Methods: The ENSCCA Registry is a multicenter observational study. Patients were included if they had a ...

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