Nociceptive Flexion Reflex Threshold is No Suitable Marker for Diagnosing Opioid-Induced Hyperalgesia

URN to cite this document:: urn:nbn:de:bvb:355-epub-581738
DOI to cite this document:: 10.5283/epub.58173

Trübenbacher, Luisa ; Lindenberg, Nicole

; Graf, Bernhard ; Backmund, Markus ; Unglaub, Wilhelm ; Lassen, Christoph L.

License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 26 Apr 2024 14:43

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Abstract

Background: Opioid induced hyperalgesia (OIH) describes a state of altered pain sensation due to opioid exposure. It often occurs among persons with opioid use disorder receiving substitution therapy. Methods: The purpose of this study was to find out, whether OIH diagnosis could be facilitated by an objective pain indicating marker: the Nociceptive Flexion Reflex (NFR). Forty persons with ...